PECULIARITIES OF TREATMENT OF CHRONIC RECURRENT APHTHOUS STOMATITIS

Аннотация

Chronic recurrent aphthous stomatitis (CRAS) is a chronic inflammatory process of the oral mucosa (OM), which occurs more often in children over 4 years of age and in adults in 10-50% of patients [1, 2]. The ongoing disease is severe and long-lasting, with frequent relapses and resistance to various treatment methods [1-3]. In today's time, the etiopathogenet of HRAS remains completely cryptogenic, and the treatment of patients with such a diagnosis is difficult; HRAS is considered as a multifactorial disease, the formation of which involves the body's autoimmune response, allergic, endocrine and hereditary factors [1-41-8 development of chronic recurrent ephthous stomatitis is associated with somatic pathologies (gastrointestinal diseases, central nervous system disorders, hypo- and avitaminosis).